Bioprocess Simulation Specialist

AI + Biology for Sustainable Ingredients

SilicoLife is a biotechnology company that harnesses the power of computational biology to sustainably produce valuable compounds through fermentation. Our proprietary technologies and expertise have been utilized by top companies in various industries for over a decade, as well as in research and development projects.

We received a Series A investment of 9.8 million euros, which is driving us towards becoming a product-focused company. This shift allows our company to exclusively focus our technology and knowledge in the creation of internal intellectual property, delivering high-value products to the high-growth supplements market.

Be part of this extraordinary journey and join us in our quest.

What’s the job?

As a DSP (Downstream Processing) / Bioprocess Simulation Specialist, you will be a crucial member of our bioprocess development team. You will apply your expertise in DSP operations and bioprocess simulation tools to design, model, and optimize downstream processes for precision fermentation and microbial cell cultures. Working closely with cross-functional teams, you will play a key role in developing scalable, cost-effective workflows that enhance our production efficiency and meet the demands of a dynamic, high-growth market.

Responsibilities

• Collaborate with R&D, process engineering, and production teams to develop and optimize DSP workflows for fermentation-based production.

• Utilize bioprocess simulation tools (e.g., SuperPro Designer, Aspen) to model processes, analyze data, and improve production efficiency.

• Design and test DSP strategies, including filtration, chromatography, centrifugation, and other purification techniques, to meet target yields and purities.

• Conduct scale-up studies and simulations to ensure reproducibility and scalability of downstream processes.

• Evaluate and mitigate risks associated with DSP methodologies and ensure compliance with regulatory standards.

• Stay up-to-date with advances in DSP and bioprocess simulation to incorporate the latest methodologies and best practices.

Benefits

Salary will be proposed considering the candidate's experience. The selected candidate will be employed by the company and will be part of an interdisciplinary team of experts in computer science, artificial intelligence, bioinformatics, systems biology, molecular biology, bioprocess engineering, protein engineering, etc.

Other benefits also include:

• Flexible work schedule: great work/life balance

• Extra vacation days over the 22 legally mandated

• Health insurance

• Flexible benefits

• Participation in internal talks, company retreats and events

• Fully-equipped kitchen with free treats and coffee

The selected candidate will be exposed to highly innovative projects, combining world-class science with disruptive business models to create sustainable and economically-viable solutions, addressing global challenges.

SilicoLife is an equal opportunities employer, committed to creating a diverse and inclusive workplace. We do not discriminate on the basis of race, gender, sexual orientation, religion, age, national origin, disability, or any other protected characteristic. We are dedicated to creating a workplace culture that values diversity, equity, and inclusion and that provides equal opportunities for all employees. We strive to foster a positive and supportive work environment for all, and we believe that everyone should have the opportunity to succeed, regardless of their background or identity. Our policies and practices reflect this commitment, and we are committed to treating all employees with respect and fairness.

The successful candidate should ideally possess:

• Bachelor’s or Master’s degree in Biological Engineering, Bioprocess Engineering, Chemical Engineering, or related field (PhD is a plus).

• Proven experience with bioprocess simulation, including DSP methods such as filtration, chromatography, and centrifugation.

• Proficiency in bioprocess simulation software (e.g., SuperPro Designer, Aspen).

• Strong analytical and data interpretation skills, ideally with experience in scaling processes for industrial applications.

• Ideally, knowledge of regulatory standards and compliance for bioprocessing.

• Excellent attention to detail and a commitment to continuous learning and innovation.